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Tumour growth prediction

The question isn't how big.
It's how fast.

For a slow-growing brain tumour, one scan tells you almost nothing on its own. What changes the plan is the trajectory, is it growing, how quickly, and when will it cross the line where you'd act.

VOLUMETRIC GROWTH MODEL 02cm³4cm³6cm³ 012mo24mo36mo48mo treat above here scans so far ● projected ◦ crosses at about 34 months

Growth tracking

Turn scattered scans
into a curve

Using a multiomics approach, with imaging data (radiomics), you can outline the tumour on every scan a patient has had, fit a growth model across them, and those loose dots become a projected line. Amalgamate this with genetics and molecular data, and we are able to build a robust prediction model. The fast-growers stand out sooner, and the stable ones can be left alone instead of pushed into surgery or another round of scans.

  • A real 3D volume on each MRI, not a diameter
  • A growth rate with a confidence band, from the patient's own history
  • A rough time-to-threshold, to set sensible scan intervals

The condition we started with

Vestibular schwannoma

our worked example
1 in 500carry one over a lifetime
Volume > width3D change shows up earlier
Watch & waitmost are monitored, not treated

Plenty of brain tumours are slow and get watched rather than treated straight away. Surgery or radiosurgery is held back for the ones that grow or start pressing on something. That makes measuring the same thing the same way, scan after scan, the part that matters most.

We started with the vestibular schwannoma: a benign tumour on the hearing and balance nerve, and a textbook watch-and-wait problem. Measuring it by volume and projecting its growth flags the fast ones earlier and spares everyone else needless intervention.

Research & development work, not a medical device or a substitute for clinical judgement.

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